Best Modern Warfare 2 ISO 45 loadout

Screenshot of Modern Warfare 2 ISO 45 on a table surrounded by loose bullets and ammo magazines
Credit: Activision


Screenshot of Modern Warfare 2 ISO 45 on a table surrounded by loose bullets and ammo magazines
Credit: Activision
October 5, 2023: Season 6 is now underway and we've tweaked the best MW2 ISO 45 loadout and the best attachments to equip.

What is the best Modern Warfare 2 ISO 45 loadout to use now Season 6 is underway? That's on the minds of fans dropping into the latest season of Modern Warfare 2 multiplayer.

While some Modern Warfare 2 guns receive adjustments as part of recent weapon buffs and nerfs, using this particular submachine gun (SMG) is a surefire way of dealing huge amounts of damage thanks to its incredible rate of fire and high damage output in close-range combat.

Before we take a closer look at the best Modern Warfare 2 ISO 45 loadout, take a look at our other guides revealing the best Tempus Razorback loadout and when the next double XP event is taking place.

What is the best Modern Warfare 2 ISO 45 loadout?

  • Muzzle: Lockshot KT85
  • Laser: 1MW Quick Fire Laser
  • Underbarrel: Merc Foregrip
  • Ammunition: .45 Auto Overpressured +P
  • Magazine: 45 Round Drum
  • Grenades: Semtex/Stun Grenade
  • Field upgrade: Dead Silence

This particular build comes with a slight improvement to damage output along with enhancements to accuracy and mobility. This guarantees your shots always hit the target no matter how quickly you're hurtling around the map during a match.

The slight hit in mobility and handling is barely noticeable, meaning this ISO 45 loadout is excellent for close-range and even mid-range engagements.

Screenshot of Modern Warfare 2 player holding ISO 45 SMG in an abandoned urban street.
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Credit: Activision

Best Modern Warfare 2 ISO 45 attachments

The gunsmith contains a wealth of attachments that allow you to build the ISO 45 to suit any play style imaginable. With running and gunning the aim of the game, this set of five is very hard to beat.

  • Muzzle: Lockshot KT85
  • Laser: 1MW Quick Fire Laser
  • Underbarrel: Merc Foregrip
  • Ammunition: .45 Auto Overpressured +P
  • Magazine: 45 Round Drum

The combination of the Lockshot KT85 muzzle and the Merc Foregrip ensures the ISO 45 is steady when firing for a prolonged period of time. For additional flinch to your target, the .45 Auto Overpressured +P ammunition distracts their aim, making them easy pickings for you.

There's nothing worse than running out of ammunition in the middle of a hectic gunfight, which is where the 45 Round Drum comes into its own. You can slay multiple opponents before having to dip out of the action to change the magazine.

Best Modern Warfare 2 ISO 45 perks and equipment

Once the best IS0 45 attachments are ready for action, picking a perk package and equipment combination is just as important if you're looking to build the strongest loadout. Here are our recommendations for the early stages of Season 5:

Perks

  • Base: Bomb Squad
  • Base: Battle Hardened
  • Bonus: Fast Hands
  • Ultimate: Quick Fix

Bomb Squad and Battle Hardened provide much-needed resistance to explosives and flash grenades that fly your way during a match. For faster health regeneration, Quick Fix allows you to stay in amongst the action for longer periods of time.

Equipment

  • Lethal: Semtex
  • Tactical: Stun Grenade

Semtex is excellent for dealing some extra explosive damage while the stun grenade is a surefire way of guaranteeing your target doesn't escape your crosshairs.

Is the ISO 45 good in Modern Warfare 2?

With plenty of other viable SMGs in Modern Warfare 2, the ISO 45 slots in towards the top of the category with ease. High mobility combined with a lethal rate of fire and high damage output is an unbeatable combination in close-quarters combat and thanks to its ease-of-use, you can take advantage of the immense power at longer distances too.

That's all there is to know about the best Modern Warfare 2 ISO 45 loadout. For more, check out the best ranked play loadouts and intel on how to unlock the Nicki Minaj Operator.

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