How to Craft Items in Resident Evil Requiem

• Primary Subject: Resident Evil Requiem
• Key Update: Dual crafting economies split between Grace and Leon
• Status: Confirmed
• Last Verified: February 26, 2026
• Quick Answer: Crafting in Resident Evil Requiem differs by protagonist. Grace uses infected blood as a shared survival currency, while Leon crafts through a traditional scrap-and-gunpowder system. Every crafting decision carries opportunity cost.

This article contains SPOILERS for Resident Evil Requiem

Crafting in Resident Evil Requiem operates through two separate systems designed to mirror the game’s dual-protagonist setup. It is not a single universal mechanic shared equally between characters.

Instead, Grace Ashcroft and Leon S. Kennedy operate within different crafting economies, each designed to reinforce their gameplay style.

Understanding how these systems work — and more importantly, how they compete with other survival resources — is essential to staying alive.

How Do You Craft Items as Grace?

For Grace, crafting revolves around infected blood, which functions as a primary survival currency.

Credit: Capcom

Once she gains the ability to harvest it, blood can be collected from environmental gore such as puddles and containers, as well as from certain defeated enemies.

This transforms parts of the environment that would normally be atmospheric detail into resource opportunities. However, collecting blood is not risk-free.

Harvesting often requires approaching corpses or contaminated areas, which can expose you to danger. As infected blood is in short supply, every unit makes a difference.

Blood doesn’t operate independently, as it’s combined with resources such as scrap gathered during exploration. Crafting typically involves combining infected blood with scrap or other components to produce useful items.

You can make handgun ammunition using scrap and a substantial supply of infected blood, showing just how blood-intensive combat crafting is.

This confirms two important mechanics, blood has tangible crafting value and crafting ammunition directly competes with other blood-based outputs.

Grace’s crafting pool also intersects with saving mechanics and survivability upgrades. In modes that require specific items to save progress, crafting resources may be used to produce those saving supplies.

That means crafting is not only useful for combat but also affects how often you can save your progress. Grace can also use the same limited resource economy to craft or unlock survivability upgrades.

How Do You Unlock New Crafting Recipes?

Recipe unlocks are part of the progression system, so players don’t have access to everything immediately.

Credit: Capcom

Recipes must be unlocked through analysis using specialized medical equipment located in certain areas.

This means crafting expands as you explore and progress. The system is built around three steps that involve unlocking blood harvesting, gathering enough materials, and analyzing or unlocking new crafting blueprints before production becomes available.

This gating prevents players from accessing the full crafting tree immediately and reinforces progression pacing.

How Is Crafting Different for Leon?

Unlike previous systems that relied on infected blood, Leon crafts items through a classic material-based approach using scrap and gunpowder.

Credit: Capcom

His crafting resembles the systems seen in recent action-focused Resident Evil entries. You collect materials, open the crafting menu, and combine ingredients to create ammunition or specialized items.

One example is the Stacked Hand Grenade, a weapon that fuses several grenades into one stronger blast. Inventory management further differentiates the two systems.

Grace operates under stricter inventory limits, meaning crafting choices are constrained by slot availability. Every item occupies space, so producing too many tools can crowd out essentials.

Leon’s attaché-case style grid allows greater flexibility, reducing some of the immediate pressure around crafting decisions.

However, crafting still consumes materials, and resources remain finite regardless of inventory size. The most important concept to understand about crafting in Resident Evil Requiem is opportunity cost.

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